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KMID : 1157520150110030191
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International Journal of Clinical Preventive Dentistry
2015 Volume.11 No. 3 p.191 ~ p.198
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The Effects of Oral Sprays Containing Prunus mune Extract and Natural Substances on Halitosis
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Hyun Yong-Cheol
Park Jung-Eun
Kwon Ha-Jeong
Jang Jong-Hwa
Yang Dal-Nim
Hwang Su-Yeon
Kim Mi-Yeon
Park Yong-Duk
Hwang Kyung-Sook
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Abstract
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Objective: The purpose of this study is to evaluate the inhibition effects of Prunus mune extract (PME) their mixtures containing green tea extract (GTE) (PME+GTE), Zanthoxylum schinifolium extract (ZCE) (PME+ZCE) on the volatile sulfur compounds (VSCs) oral pathogenicity microorganisms.
Methods: The amount of the VSCs and oral microorganism in the mouth of fifteen volunteers who healthy Koreans were measured by Sensor Gas Chromatograph ODSA-P2 (FIS Inc., Hyogo, Japan) and real-time polymerase chain reaction, respectively.
Results: The average concentration of oral VSCs was lower in the PME+GTE and PME+ZCE group, especially, the VSCs in PME+ZEC group was statistically decreased compared to the control group. Among the oral bacteria, Tannerella forsythia was not detected in PME, PME+GTE group after 2 weeks, and Prevotella intermedia was significantly inhibited in each group.
Conclusion: All experimental sample showed the inhibition effects on the oral VSCs, the cause of halitosis, especially, the inhibition effect of PME＋GTE and PME＋ZCE groups were higher than PME group.
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KEYWORD
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prunus mune, green tea, zanthoxylum schinifolium, halitosis, oral sprays
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